GLP-1 is a hormone-like peptide that is naturally found in the body and plays a significant role in appetite regulation and weight control. In a weight loss program, a synthetic analog of GLP-1 is used to help reduce appetite and promote satiety, which can help decrease food intake and ultimately lead to weight loss.
GLP-1 is typically administered as a subcutaneous injection, meaning under the skin, using an insulin pen or a special syringe. The dosage and frequency of injections vary depending on the specific program and the doctor’s recommendations.
GLP-1 acts at various sites in the body to help reduce appetite and promote weight loss. It stimulates the release of insulin in the pancreas, which lowers blood glucose levels and promotes satiety. It also slows gastric emptying, which makes food move more slowly through the gastrointestinal tract and prolongs the feeling of fullness. In addition, GLP-1 acts in the brain to reduce appetite and increase the sense of fullness.
Appropriate candidates for a GLP-1 weight loss program are typically adults with a body mass index (BMI) of 30 kg/m² or higher, or with a BMI of 27 kg/m² or higher with weight-related conditions such as type 2 diabetes or high blood pressure, who have not been successful with other weight loss approaches and are under the supervision of a doctor.
Like any medication, a GLP-1 weight loss program may have side effects. Some of the possible side effects include nausea, vomiting, diarrhea, constipation, abdominal pain, injection site reactions, and rarely, pancreatitis. It’s important to talk to a doctor if you experience side effects to receive proper evaluation and adjust the treatment if necessary.
The amount of weight that can be lost with a GLP-1 weight loss program varies depending on individual factors such as starting weight, adherence to the program, and overall lifestyle changes. Studies have shown that GLP-1 analogs can lead to significant weight loss, typically ranging from 5% to 10% of initial body weight over a period of several months. However, individual results may vary.
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